Thesis & Dissertation

Permanent URI for this communityhttp://10.0.2.76:4000/handle/123456789/2

Browse

Filter results by year or month
Now showing 1 - 20 of 52
  • Thumbnail Image
    Item
    A morphological study of Human Calcanei and their Articular facets
    (SRHU, 2006) Cheema, Harvind Singh
    The present study was conducted on 200 North Indian calcanei to assess the gross morphological features with special emphasis on the dimensions and configurations of the talar articular facets. The data obtained was compared with the results of the earlier studies to provide these values for future comparative studies.
  • Thumbnail Image
    Item
    Lip prints as a method of Identification
    (SRHU, 2007) Bindal, Umesh
    Lips are two fleshy folds sunounding the oral orifice. It has many elevations and depressions forming a characteristic pattern called lip prints. The figure formed by these sulci was called "figura linearum labiorurn", i.e. in general "lip prints". The examination of which is referred to as cheiloscopy. The present study was carried out over the lip prints as a means of identification since it differs from person to person and remains unchangeable throughout life.
  • Thumbnail Image
    Item
  • Thumbnail Image
    Item
  • Thumbnail Image
    Item
    Study of Pantoprazole on Gastrointestinal Mucosa of Albino Rats
    (SRHU, 2010) Dass, Praveen Kumar
  • Thumbnail Image
    Item
  • Thumbnail Image
    Item
    A study 0f placental Morphology and histology in Hypertensive pregnancies and its correlation with foetal Outcome
    (SRHU, 2014) Pasricha, Navbir
    The study of the placenta is, by necessity retrogressive in nature. Yet it provides a reflection of the hazards, the foetus has undergone, during its growth and development.
  • Thumbnail Image
    Item
    Histological study of urinary system In developing human fetus
    (SRHU, 2015) Kaur, Harmeet
    ThisstudywasconductedintheDepartmentofchatomy,Himalayan InstituteofMedicalSciences,SwamiRamaHimalayanUniversity.Prenatal development is a crucial period for human development of the urinary system. It is a complex process and proceeds precisely in an orchestrated mamerwithaseriesofmolphologicalandhistologicalevents.
  • Thumbnail Image
    Item
    Histological Study of Cerebral Cortex in Human Fetuses
    (SRHU, 2016) Jagdish, Prerna
  • Thumbnail Image
    Item
    Morphological and Histological Study of liver, gall bladder and Bile ducts in human
    (SRHU, 2018) Agnihotri, Devika
    We conducted out study in the department of Anatomy, HIMS over a period of one year. The study comprised of 32 aborted human fetuses of varying gestational age which were procured from the department of Obstetrics and Gynaecology, I.HMS. The abdomens were dissected and the liver, gall bladder, cystic duct and the common bile duct were removed and fixed with formalin. We have studied the external parameters of the liver, gall bladder, cystic duct and the common bile duct. Sections were taken from all the four organs and stained with H&E, Masson's Trichome and PAS and observed for the developmental changes.
  • Thumbnail Image
    Item
    A morphological and Histological Study of developing human fetal Cerebellum
    (SRHU, 2019) Ahmad, Nadia
    The current study is an effort to build a timeline for the different morphological and histological changes occurring in developing human fetal cerebellum. It would be helpful to the forensic experts to roughly estimate the gestational age in medicolegal cases, especially in cases where gestational age estimation is required from only a few remains of the brain tissue. Moreover, any deviation from the normal timeline of events would indicate the development of some pathology.
  • Thumbnail Image
    Item
    Study to assess the effectiveness of yoga on stress level and quality of life of breast cancer patients undergoing chemotherapy
    (SRHU, 2022-07-09) Prakash, kamli
    Background: Among cancer of different organs in the body, the carcinoma of the breast is highest in occurrence worldwide, after lung cancer. The treatment of cancer and cancer itself cause many side effects and complications, which affect the quality of life (QOL) and cause a considerable consequence on Health Related QOL (HR-QOL) in common. While going through cycles of chemotherapy, breast cancer patients experience many side effects such as nausea, vomiting, weakness, anemia, and alopecia. Supportive or complementary therapies such as yoga, are easy to administer, economical, and useful in reducing the adverse effects of cancer treatment and helpful in enhancing the quality of life of patients with cancer. Objectives: To determine the effectiveness of yoga on the stress level & quality of life of breast cancer patients undergoing chemotherapy Materials and Methods: Quantitative Research approach with Randomized Clinical Controlled Trial & Time series design was adopted in this study. The consecutive sampling technique was used to recruit 100 breast cancer patients fulfilling the eligibility criteria and undergoing chemotherapy in Cancer Research Institute, Swami Rama Himalayan University. The recruited patients were randomized to control (N=52) and experiment (N=48) group by concealed randomization. The informed written consent was taken from each participant. The baseline data was collected during first cycle of chemotherapy with Anxiety, Depression, Stress Scale and EORTC QLQ-C30 (version 3) & BR23. The participants in experimental group were taught diaphragmatic breathing, systematic relaxation and alternate nostril breathing, joints and glands exercises of neck and shoulder. They were instructed to practice twice daily at home. They were supervised in practicing these when they were receiving second, third, fourth, fifth and sixth cycles of chemotherapy. The participants in the control group received routine care. The data was again collected during second, third, fourth, fifth and sixth cycles of chemotherapy. Results: The sample in both groups had similar demographic and clinical characteristics. They had similar anxiety, depression & stress and quality of life scores during first cycle of chemotherapy. The mean depression scores of breast carcinoma patients belonging to the control group remained almost the same over a period of six cycles. However the depression scores of the experimental group decreased significantly from the baseline in all six cycles. The mean xvi scores of the physical function for the control group decreased significantly from the baseline score in the second through the sixth cycle, whereas, scores of the experimental group decreased only in the fourth cycle. The mean scores of the emotional function of both experimental and control groups decreased significantly from the baseline score in the 3rd, 4th, 5th and the 6th cycles. However, the control group had a greater decrease in scores compared to the experimental group. The fatigue scores increased more in control group compared to the experimental group. The mean scores of body image of the experimental and the control group decreased significantly from the baseline score in the second through the sixth cycle. However, the experimental group revealed statistically significant variation from the control group in the third and fifth cycles. The mean scores of future perspectives of patients in the control group decreased in the second through the sixth cycle from the baseline score. In the experimental group the mean scores increased significantly in the second through the sixth cycle from the baseline score. Conclusion: The yoga was effective in decreasing symptoms of depression, improving the quality of life of breast cancer patients in the experimental group in the areas of global health status, physical function, role function and emotional function, perception of body image and future perspectives and decreasing the symptoms of fatigue, insomnia, loss of appetite, constipation, during the period of chemotherapy.
  • Thumbnail Image
    Item
    Study of environmental carcinogens interference in bio molecular kinetics of cell cycle regulatory machinery using systems biology approach and their protection by nano particles
    (SRHU, 2022-09-07) Kumari, Anukriti
    Incidents of cancer are increasing each year and lung cancer and head and neck cancers contribute to majority of deaths related with cancer. Environmental carcinogens are leading cause of lung cancer and head and neck cancer. BaP and NNK are the most dangerous environmental carcinogens which have been placed in group 1 category of carcinogens by IARC. Industrial and vehicle exhausts, tobacco smoke, pyrolysis of various organic matters are the major sources BaP. NNK is found in abundance in various types of tobacco related products like cigars, cigarettes, tobacco snuffs etc. It also gets formed endogenously in the saliva of people who come in contact of nicotine because of the reaction between salivary nitrate and nicotine. In this study we have tried to identify the major biomolecular targets of BaP and NNK using various tools of systems biology. We have also tried to analyze the scavenging and protective potentials of carbon nanoparticles (Single walled carbon nanotubes, multiwalled carbon nanotubes and fullerenes) against these environmental carcinogens (BaP and NNK) with the help of molecular docking simulations and adsorption load analysis. x Objectives: To fulfill the aims of our study, we have divided the study into four objectives Objective 1: Identification of most probable biomolecular targets of environmental carcinogens (BaP & NNK) among the cell cycle regulatory proteome once they enter the biological system. Objective 2: Construction of network system for functional coverage of most potent biomolecular targets of environmental carcinogens among the cell cycle regulatory proteome. Objective 3: Designing of cell cycle regulatory bio-model along with its kinetics and determining the impact of environmental carcinogens on normal cell cycle regulation. Objective 4: Determination of the binding efficiencies of environmental carcinogens with carbon-based nanoparticles, environmental carcinogens adsorption load over nanoparticles and comparison of binding efficiencies of carcinogens with their biomolecular targets and nanoparticles. Methodology: For finding the genes hampered by BaP, T3DB database was used and Pubmed was used for finding the genes that get hampered by NNK by using various keywords like NNK, humans, cancer, cell cycle etc. Once the genes were identified, proteinxi protein interaction networks were generated with the help of STRING.db software. The networks were analyzed with the help of Cytoscape software. Modulation and enrichment analysis were done using MCODE and ClueGO apps of the cytoscape software. Seed proteins were identified from the clusters generated by MCODE and then network were generated using these seed proteins for BaP and NNK separately. The nodes present in both the BaP and NNK rewired PPINs were analyzed on the basis of their topological properties like degree, clustering coefficient, betweenness score and bottleneck scores. To further screen out the proteins, molecular docking simulations were performed on all the selected proteins for BaP and NNK. Once top bio-molecular targets were identified for BaP and NNK, cell cycle regulatory model was designed using cell designer software and then SBMLsqueezer was used to incorporate the biokinetics in the model. Time course analysis was performed using COPASI software and changes in concentrations and fluctuations in the oscillations were analyzed. Finally, we tried to analyse the scavenging capacity of carbon nanoparticles (SWCNT, MWCNT and Fullerenes) by comparing the binding efficiencies of carcinogens and carbon nanoparticles with that of carcinogens and their top bio-molecular targets and finding the adsorption load capacity of carbon nanoparticles for BaP and NNK. Results: 4000 genes were found to be hampered by BaP where as 544 genes were extracted from Pubmed that were hampered by NNK. QSOX1, PTGS2, NOS2 were the xii top three biomolecular targets for BaP. CDK7, CCNA1 and CDKN1B were the top biomolecular targets for NNK. On the analysis of the scavenging potentials of SWCNTs, MWCNTs and Fullerenes against BaP and NNK, it was found that MWCNT had the highest scavenging potential against BaP and showed highest adsorption capacity while for NNK, SWCNT showed the highest binding energy and MWCNT showed the highest adsorption load capacity. Conclusion: QSOX1, PTGS2 and NOS2 came out to most influencing key regulatory biomolecular targets which may govern whole BaP associated interactome while CDK7, CCNA1 and CDKN1B were the most influencing key regulatory biomolecular targets which may govern whole NNK associated interactome. Out of all the three carbon based nano-particles used to scavenge BaP and NNK, MWCNT has the highest binding affinity as well as adsorption capacity against BaP while for NNK, SWCNT showed highest binding affinity and MWCNT showed highest adsorption capacity.
  • Thumbnail Image
    Item
    Effectiveness of Home Based Newborn Care HBNC on knowledge attitude and practices among ASHAs Accredited Social Health Activists working in rural areas of Uttarakhand
    (SRHU, 2022-09-07) Devi, Rajkumari Sylvia
    Neonatal mortality stays high regardless of a decline in under-five deaths. About 40% of all under-five deaths are among infants.1 Almost all (99%) of these neonatal deaths were happened in developing nations with the most elevated rates in sub-Saharan Africa.2 More than 50% of child deaths occur below the age of five years. In 2008, the number of death of under-five children was 1,829,826 out of which 1,003,767 (54.8%) died in the neonatal period. Preterm birth, neonatal infections, asphyxia, sepsis, diarrhea, malnutrition, etc. are the main reasons for most neonatal deaths.3-5 India ranks second with the largest population, accounting for about 17% of the global population and 20% of worldwide births. India accounts for a fifth of the global under-five child death. Around 27 million live births and two million deaths of under-five children are reported each year. The annual mortality rate of under-five children in India represents a quarter of the global child mortality. Therefore control of child death is very crucial if the world is destined to achieve the targeted Sustainable Development Goal (SDG).6 Indian Academy of Pediatrics (IAP) has critically examined numerous health programs of children started by state and central government. Mission 20/20 by IAP has come up to further decrease IMR. With this mission, IAP conveys its zeal to commit its endeavors and assets to catalyze the decrease of IMR in India. This activity supports all necessary requirements to achieve the objective of the mission, IMR of 20 by 2020.7 2 The present neonatal mortality rate is still far from achieving the targeted goal of less than 20/1000 live births.8 Control of neonatal death is crucial to attain the targeted sustainable development goal of WHO. The government of Indian, through the Ministry of Health and Family Welfare (MoHFW) and the National Health Mission (NHM), has initiated various health programs to control newborn mortality in both villages and cities.9-10 Under the scheme “Janani Suraksha Yojana”, institutional deliveries have been intended to improve by health professionals through cash rewards to the mothers.9,11 This may further encourage providing children with good food and quality health care. However, the achievement concerning the control of neonatal mortality rate is still far from the targeted rate. Significant inequalities of NMR are found in rural and urban, and different socioeconomic classes. The neonatal mortality in villages is just double as compared to developed cities (31 vs 15 per 1000 live births).8 The failure may be due to the way of functioning of the health departments. At this point of time, it is imperative to execute sincere and collaborative services from all related departments i.e. government and private health sectors, and society organizations. Various factors influence the survival of children after birth that include proper breastfeeding, maintaining a warm body temperature, periodic medical check-ups and getting treatment, etc. The early few years of birth of children is a stage of life where possible maximum care must be provided as they are exposed all of a sudden to a polluted external environment from the sterile condition. The children need to be protected in all respects in the new environment. As a result, a huge number of neonates fall under prey in economically least developed and developing countries. Under-five 3 deaths are mainly due to premature birth, neonatal sepsis, birth asphyxia, pneumonia, diarrhea, etc in rural areas of India.12-13 Efforts have been made to reduce the death rate by incorporating new strategies with respect to premature birth, asphyxia, pneumonia, etc. in several child survival programs.14-17 Reports are available on the successful implementation of some effective measures related to child health care being taken up by rural health care workers. Management of pneumonia in under-five children using cotrimoxazole could result in a 20% reduction in neonatal mortality that hints the importance of possible home-based care in the management of child mortality
  • Thumbnail Image
    Item
    Isolation identification and drug resistance testing of gram negative bacilli at a tertiary care hospital with special emphasis on the phenotypic and genotypic characterization of carbapenem resistance
    (SRHU, 2022-09-07) Khanduri, Naresh
    The study included specimens from OPD and IPD patients of all age groups and both sexes. Specimens were cultured on suitable media. Isolates were identified by biochemical methods, both in house and by VITEK 2. Susceptibility to carbapenem drugs (imipenem, meropenem and ertapenem), as well as ampicillin, amoxycillinclavulanate, ampicillin-sulbactam, piperacillin-tazobactam, cephalothin, cefoxitin, cefotaxime, ceftazidime, cefepime, aztreonam, gentamicin, amikacin, ciprofloxacin, levofloxacin, co-trimoxazole, tetracycline, tigecycline, chloramphenicol, and colistin performed by Kirby-Bauer disc diffusion method. A total of 1544 isolates of Gram negative bacilli were studied from different specimens, of which 184 were resistant to one or more carbapenem drugs. Acinetobacter calcoaceticus baumannii complex (104 isolates; 52%) was the dominant species, followed by Pseudomonas aeruginosa (31 isolates; 15.5%). Among the 49 isolates of Enterobacteriaceae, K. pneumoniae was the commonest with 17 (34.6 %) isolates, followed by E. coli with 15 (30.6 %) isolates. Most carbapenem-resistant GNB came from the intensive care units and the neurosurgery ward. The largest numbers of carbapenem-resistant isolates were isolated from pus, urine, and endotracheal tube aspirates. Carbapenem-resistant isolates were generally also resistant to most other antimicrobials except tigecycline and colistin. False-positive carbapenem-resistance Six (10.9%) Enterobacteriaceae isolates appeared to be carbapenem-resistant upon testing with the Kirby-Bauer disc diffusion technique with discs procured from HiMedia. These isolates later turned out to be sensitive when retested with the Kirby-Bauer disc diffusion technique with discs procured from Rosco Diagnostica, Denmark, and also by the Etest method, resulting in a false-positivity rate of 10.9% for disc diffusion. In addition, four isolates of Stenotrophomonas maltophilia and six isolates of Elizabethkingia meningoseptica had to be left out of the study because they are intrinsically resistant to carbapenem Minimum Inhibitory Concentration The Etest method for minimum inhibitory concentration (MIC) showed that the carbapenem MICs of most resistant isolates were ≥32 μg/ml. The remaining 184 isolates were then tested for carbapenemase enzymes and efflux pumps by phenotypic and genotypic methods. PHENOTYPIC METHODS Modified Hodge Test (MHT) Of the 184 isolates tested by MHT, only 22 tested positive. Rosco KPC and MBL detection kit Of the 49 Enterobacteriaceae isolates, 40 were MBL positive, 2 were both MBL and KPC positive and the remainder did not produce any of the enzymes and were presumed to be resistant by other mechanisms. Rosco Rapid CARB Blue kit 43 (41.3%) Acinetobacter, 13 (41.9%) P. aeruginosa & 39 (79.5%) Enterobacteriaceae isolates showed the presence of carbapenemases by this kit. Rosco Neo Rapid CARB kit The Enterobacteriaceae and Pseudomonas isolates were then tested by Rosco neo rapid CARB kit. 40 (81.6%) Enterobacteriaceae isolates and 16 (51.6 %) P. aeruginosa isolates were tested positive as carbapenemase producers Carba NP test, CarbAcineto NP and Blue Carba tests with modifications Overall 45 (91.8%) Enterobacteriaceae and 19 (61.2%) P. aeruginosa isolates were found to be positive for carbapenemase production by Carba NP and Blue Carba tests Overall 84.6% Acinetobacter calcoaceticus baumannii were positive by CarbAcineto NP and Blue Carba test for the carbapenemase detection. In terms of modifications, no difference in results was found regarding the source of imipenem while in three (6.25 %) Enterobacteriaceae isolates carbapenemase production was found to be inducible by imipenem Carbapenem inactivation method (CIM) Of the resistant isolates, 73 (70.1%) Acinetobacter spp., 15 (48.3%) P. aeruginosa and 38 (77.5%) Enterobacteriaceae isolates were tested positive for carbapenemase activity by this test. GENOTYPIC METHODS Detection of different carbapenemase genes Majority of the isolates showed the presence of NDM-1 carbapenemase gene. In addition to NDM-1gene, the isolates also showed the presence of VIM and OXA-48 genes. Majority (83.3 %) of the VIM positive were P. aeruginosa. OXA-48 was detected in only K. pneumoniae isolates. None of the study isolate found to be positive for KPC gene. EFFLUX PUMP ACTIVITY The presence of efflux was detected by two methods namely ethidium bromide cartwheel method and agar dilution method using reserpine as efflux inhibitor Ethidium bromide cartwheel method On performing the efflux protocol 27 isolates were found to be positive. i.e. (the strains showing little or no fluorescens under UV light) Reserpine as efflux pump inhibitor Only 20 isolates showed a decrease in the MIC of meropenem when reserpine was added.
  • Thumbnail Image
    Item
    Post traumatic stress disorder ptsd and quality of life qol of natural disaster victims of uttarakhand
    (SRHU, 2022-09-07) Mahalingam, V.
    Introduction In view of catastrophe happen in disaster prone Uttarakhand, its poor preparedness and severe outcome in terms of destruction and loss of human lives & property, a study was designed to look into other 'not too visible' areas loss in terms of Post-Traumatic Stress Disorder (PTSD) and Health related Quality of Life (H-QOL) of the disaster victims and estimate this burden. Hence, the present study was planned to estimate magnitude/prevalence of PTSD and assess Health related QOL with potential relationship between variables of PTSD & Health related QOL among the disaster victims of Sub Himalayan Uttarakhand state of India . Methods: The research design adopted had both Quantitative and Qualitative as it was most appropriate to attain the data from the Disaster victims. Quantitative component of the study design was used to assess Prevalence of PTSD and post Disaster H-QOL among the afflicted. The Qualitative component study design was used to do SWOT analysis on ongoing disaster preparedness and mitigation process. Data collection was done in two different time intervals i.e. Six month after disaster (Baseline) and eighteen month after disaster (End line). At baseline 2667 disaster victims were sampled by multi stage probability sampling in a cross sectional study with key respondents being head of the family , next to head of the family, any individual directly injured during disaster, aged ≥14 years and non-alcoholic were included in the study. Among the baseline disaster victims 1719 of them were given responses about PTSD and HQOL at end line. Total of fifteen (15) ASHA workers were selected who were already staying in the village with disaster victims to collect the data. Focus group discussion and in depth interviews were been done to generate information for SWOT analysis on ongoing disaster preparedness and mitigation process. Instruments used were PCL-S and WHOQOL- BREF tools besides a structured, pre-tested instrument to elicit socio- demographic data. The purpose of the study was explained and written informed consent was obtained from the study participants. Results: ➢ More than half (51%) of the disaster victims were diagnosed with PTSD at the Baseline. ➢ End line prevalence showed that every fifth (22%) disaster victim met the criteria of PTSD symptom and 78% of disaster victims overcame the stress. ➢ The base line PTSD mean score is significantly higher than the end line PTSD mean score at the level of significance p≤.05. ➢ At baseline the overall H QOL score was found to be ‘poor’ (1.76±.43). Sub scales of H QOL like physical (2±.03); social (2±.02) and environmental H–QOL (2±.01) were found to be ‘poor’. And psychological domain of H- QOL of disaster victims was found to be ‘very poor’ as it was 1.1±.40. ➢ Total H QOL score at end line was found to be improved from the baseline 2.53±.43 and it was ‘neither poor nor good’. Other domains like physical (3.02±.06), Social (3.7±.71) showed improvement. The radical improvement was seen in environmental (4.1±.05) domain. Even though psychological domain was also found to be nominally improved from ‘very poor’ to ‘poor‘ (1.9±.30). ➢ The total H QOL score across all domains indicates significant improvement in symptoms at the end line (2.53±.43) at the significant level of p ≤.05. ➢ Health related QOL was found to be negatively correlated with PTSD among the disaster victims. ➢ Socio-demographic and other variables, namely gender, education, occupation, family income, marital status, kind of disaster exposed to, frequency of disaster, type of loss and type of exposure significantly contributed development of PTSD. ➢ Except duration of disaster exposure all socio-demographic and other variables, like gender, education, occupation, family income, marital status, kind of disaster exposed to, frequency of disaster, type of loss and type of exposure significantly affected the Health related Quality of Life of Disaster victims. Conclusion: ➢ The findings of study highlight requisite need for identification and intervention for PTSD for Disaster Victims in context of developing countries. ➢ The scope of the study may be extended into a larger sample and coverage area; the initiative has the potential to be replicated at socio-epidemiological state with similar perspective. ➢ PTSD may persist for several years after a disaster that may result in various functional impairment in affected people both physically and psychologically. ➢ Required treatment program should be organized to cure post-disaster stress along with assessment, diagnosis and interventions for survivors should be taken as priority goal in a program of public health. ➢ Both community and provider capacity unit for disaster-preparedness and mitigation system should be built. Imparting appropriate coping skills to deal with post disaster affects via proper designed modules is an imperative need. ➢ Research studies can also test whether treatment targeting PTSD symptoms have a beneficial effect on HQOL and whether interventions specifically effectively reduce PTSD symptoms. ➢ State and central government authorities need to focus on minimizing the damage to existence, belongings and surroundings before the catastrophe moves.
  • Thumbnail Image
    Item
    Psycho behavioral determinants affecting quality of life of staff nurses posted in critical vs non critical units
    (SRHU, 2022-09-07) Sharma, Rakesh
    itical unit and vice a versa for the duration of 2 months. After completion of 2 months they were re-shifted to their original units. Data were collected with self-reported questionnaires included demographic proforma to collect personal and professional characteristic of staff nurses, MBI-HSS to assess burnout level, and WHOQOL-BREF to assess quality of life. A computerised stress profile test (CSPT) was conducted to record heart rate, GSR value and skin temperature of study participants posted. Burnout and quality of life of staff nurses were assessed at baseline, every 15th day during change in posting and after re-shifting at 15th and 30th day. A computerised stress profile test (CSPT) was xiv conducted at base line and at 60th day during change in the posting. Data was analyzed and interpreted by using descriptive as well as inferential statistics. Statistical analysis was done with the help of SPSS-22 for Windows. Results: At baseline scores of psycho-behavioral determinants were higher and lower quality of life among staff nurses working in critical unit then the non-critical units (p0.05). There was a reduction in scores of psycho-behavioral determinants and increase in quality of life scores of staff nurses after shifting to non-critical units from critical units (p0.05). After change in posting of staff nurses from non-critical to non-critical units, their scores of psychobehavioral determinants was significantly increased and reduced in the scores of quality of life (p0.05). Conclusion: It is an important area to identify the levels of emotional outcome as a burnout among staff nurses and quantify them with physiological parameters, which affect their quality of life. A change in work unit was a significant strategy to reduce levels of burnout, improve in physiological parameters and finally improved in quality of life of staff nurses working in critical unit.
  • Thumbnail Image
    Item
    Estimation of Foetal cephalic index in Utero during various periods of Pregnancy by Ultrasonogram and their correlation to gestational age In the Garhwali population
    (SRHU, 2022-10-16) Puri, Rashmi
    Estimation of the exact date of confinement by the obstetricians has been for a long time calculated by the Nagele's rule (LMP plus 7 days minus 3 months). Estimation of an accurate gestational age is essential by which an obstetrician will be successful in managing an antenatal patient. Many a times the patients do not remember their exact date of LMP. Estimation of gestationalage on the basis of measurement of the biparietal diameter by the ultrasonographic methods is being followed in most of the hospital.Various workers like Hadlock et al6, Berger et al2°, Dewhurst et a|2', Sabbagha eta| 23 Campbell 24, Parker et a| 26, Dubowitz and Goldberg et al 27, Okupe et a| 28, Varma 32 have observed the changes in the BPD at various gestational ages. They have also laid down the various table by which gestational age can be estimated by a given BPD.
  • Thumbnail Image
    Item
    Effect of formalin on respiratory system of albino rats: A histological study
    (SRHU, 2022-10-25) Gupta, Monika
    Formaldehyde (formalin) is a widely used industrial chemical and is also present in vehicle emissions & embalming fluid. Widespread occurrence of formaldehyde alarmed scientists to see its possible effects on living systems. In a number of previous studies, it was found genotoxic and carcinogenic to animals including rats, monkeys and hamsters etc. Multiple studies were also done on humans to see its possible carcinogenic effects. This study was conducted to see the histological effects of formalin on the respiratory tract of albino rats. 60 rats were taken for the experiment which were divided into 3 groups. 6 rats were used as controls while 3 subgroups of 18 rats each were exposed to formalin inhalation for 9, 18 and 36 days respectively.
  • Thumbnail Image
    Item
    Dermatoglyphics in type II diabetes mellitus
    (SRHU, 2022-10-25) Srivatsva, Shubha
    Dermatoglyphics in type H DM has been studied with views to jdentjfy significance of dermatoglyphics for early detection of patients with type H DM and identjfyjng normal people who are prone to Type 11 DM.